Fundamentals of Genomics and Proteomics in Neuroscience

To introduce students to the techniques and research fields of genomics and proteomics, as well as their applications in basic and clinical neurosciences.

Lectures:
1.Introduction to genomics and proteomics in neuroscience.
2.Genome sequencing.
3.Genomes as the basis of biology and neurobiology.
4.Mapping, sequencing, annoatation and data bases.
5.Comparative genomics.
6.Evolution and genomic change.
7.Genome expression and microarrays.
8.Proteomics.

Basic bibliography
- Lesk A. (2017) “Introduction to Genomics” (3rd ed). Oxford Univ. Press.

Complementary bibliography
- Cooper GM. 2021. La Célula, 8ª Edición, Marbán.
- Klug et al. (2018) “Concepts of Genetics” (12th edition). Pearson Education, Inc.
- Pevsner J. (2015) “Bioinformatics and Functional Genomics” (3rd ed). Wiley-Blackwell.
- Twyman RM. (2013) “Principles of Proteomics (2nd ed)” Garland Science.

- The student will acquire knowledge in the fields of genomics and proteomics in neuroscience.
- The student will learn the genetic basis of nervous system diseases.
- We will describe the basic principles of the use of genomic and proteomic tools in neuroscience research

Lectures from the professor and seminars presented by the students based in original scientific publications or recent reviews.

- Attendance and active participation in class discussions (10%)
- Critical discussion and presentation in the seminars (40%)
- Test of the 8 study units (50%)

Lectures 25 hours.
Seminars 2 hours.
Tutorials 3 hours.
Total in presence hours 30.

Personal study 30 hours.
Presentation and essay 15 hours.
Total number of hours of personal work 45.

Subject of interest for students who wish to increase their knowledge on the molecular and genetic bases of nervous system disorders (neurologic and psychiatric), as well as the applications of genomic and proteomic technologies in basic neuroscience.

Para los casos de realización fraudulenta de ejercicios o pruebas será de aplicación lo recogido en la “Normativa de avaliación do rendemento académico dos estudantes e de revisión de cualificacións”.