ECTS credits ECTS credits: 6
ECTS Hours Rules/Memories Student's work ECTS: 99 Hours of tutorials: 3 Expository Class: 24 Interactive Classroom: 24 Total: 150
Type: Ordinary Degree Subject RD 1393/2007 - 822/2021
Center Faculty of Nursing
Call: Second Semester
Teaching: Sin Docencia (En Extinción)
Enrolment: No Matriculable (Sólo Planes en Extinción)
New advances in scientific knowledge mean that the causes of diseases are formulated, more frequently, at the molecular level. The study of this subject must serve the student to:
1. Know the vocabulary and basic terminology of Biochemistry.
2. Acquire the basic knowledge of Biochemistry and understand the complexity and functioning of biological processes at the molecular level.
3. Know the main chemical and structural properties of biological macromolecules, as well as the relationship between these properties and the various functions they perform.
4. Understand the molecular mechanisms used by living beings in the development of their functions, mainly in the processes of transduction and energy storage, biosynthesis and use of precursors, information routes, as well as the regulation of these from an integrated perspective.
5. Develop the ability to integrate the knowledge provided by this and other related subjects, and the ability to compare and relate concepts, in order to apply them to different clinical problems.
6. Understand the impact of Biochemistry and Molecular Biology in today's society and its applications in the field of health.
7. Develop the capacity for autonomous learning.
8. Demonstrate reasoning ability, argumentation and memorization of the basic aspects of the subject.
9. Acquire familiarization with the main sources of information, both traditional and through new technologies, and demonstrate training to critically select the information.
10. Demonstrate ability to work as a team, with initiative to solve problems through the integrated application of the knowledge acquired, and flexibility before the contributions of colleagues.
11. Demonstrate the capacity to elaborate, present and publicly defend a work.
THEORETICAL CONTENT
1 - CARBON, LIPID AND PROTEIN HYDRATES: concept and properties. Composition and classification. Structure and function
2 - ENZYMES: Classification. Coenzymes. Specificity Active center Catalysis mechanism. Enzymatic inhibition Regulation.
3- METABOLISM: Basic concepts and overview. Catabolism Anabolism. Metabolic pathways Oxidation-reduction reactions. High energy phosphate compounds.
4- GLUCOLYSIS: Phases and energy balance. Regulation. Pathways of incorporation of fructose and galactose. Destinations of pyruvic acid.
5- CITRIC ACID CYCLE: Sources and destinations of Acetyl Coenzyme A. Reactions of the citric acid cycle. Anaplerotic routes. Regulation.
6 - ELECTRONIC TRANSPORT CHAIN and OXIDATIVE FOSFORILATION.
7- GLUCONOGENESIS: glucose synthesis. Regulation glucolisis-gluconeogénesis
8 - BIOSYNTHESIS AND DEGRADATION OF GLUCOGEN: Stages. Coordinated regulation.
9 - ROUTE OF THE PENTOSAS PHOSPHATE. Regulation
10- LIPIDIC METABOLISM I: Sources and mobilization of fatty acids. Oxidation of fatty acids. Energy balance.
11 - LIPIDIC METABOLISM II: Synthesis of fatty acids and storage. Ketone bodies. Metabolism of lipoproteins.
12- METABOLISM OF AMINO ACIDS: Metabolic destinations. Transamination. Desamination Nitrogen transport. Urea cycle. Routes of degradation of amino acids.
13- METABOLISM OF THE NUCLEOTIDES: General functions. Purine nucleotides. Pyrimidine nucleotides.
14 - METABOLIC INTERRELATIONS: Overview. Liver metabolism in a state of good nutrition and starvation. Metabolic interrelations between tissues.
15 - DNA REPLICATION AND REPAIR.
16- TRANSCRIPTION of genetic information. Ripening of RNA
17 -TRADUCTION: Protein synthesis. Post-translational processing.
18- REGULATION OF GENE EXPRESSION.
Basic bibliography:
MEDICAL BIOCHEMISTRY. 5th Edition - 2019. John W. Baynes, Marek H. Dominiczak. Publisher: Elsevier
LEHNINGER. PRINCIPLES OF BIOCHEMISTRY. 7th Edition- 2018. Nelson, D. - Cox, M. Editorial OMEGA
BIOCHEMISTRY. With clinical applications. 7th ed-2015. Stryer, L. Berg, J. M. Tymoczko, J.L .. Ed. Reverté.
BIOCHEMISTRY. The molecular bases of life. 7th ed-2020. McKee, T - McKee, J.R. Editorial MCGRAW HILL.
BIOCHEMISTRY. Denise R. Ferrier 7th ed- 2017. Editorial Wolters Kluwer.
MARKS BASIC MEDICAL BIOCHEMISTRY. A clinical approach. 5th ed- 2018. Lieberman, M. Peet, A. Editorial Wolters Kluwer.
NETTER. ESSENTIAL BIOCHEMISTRY. 1st ed- 2019. Roner, P. Editorial ELSEVIER
COMPETENCES RELATED TO THE MATTER
(* ORDER CIN / 2134/2008, + Book branco da ANECA do Titulo de Grao de Enfermaría)
Know and identify the structure and function of the human body *.
Understand the molecular and physiological bases of cells and tissues *.
Relevant knowledge of and ability to apply basic and life sciences +.
Relevant knowledge and ability to apply problem solving and decision making +.
INTERPERSONAL COMPETENCES
Communication skills
Interpersonal skills
Capacity for teamwork
EXPOSITORY TEACHING
As this is an extinct subject, it should be noted that expository teaching is not offered. The content that enters the final exam of this class is indicated in the Theoretical Contents section and does not vary with respect to the 2021-2022 academic year, the last academic year this class was actively taught.
INTERACTIVE TEACHING
The regulations contemplate two modes of action with respect to interactive teaching for subjects in extinction
a) Students who have taken and passed the continuous assessment in previous courses are exempt from doing interactive teaching, since their previous assessments will be maintained.
b) Students who have not taken the interactive part of the class in extinction can join the interactive teaching of the corresponding subject in the new study plan.
It is essential that the student contact the teacher at the beginning of the academic year to facilitate said incorporation.
The final test related to the THEORETICAL CONTENT represents 60% of the total grade (6 points)
The exam will be mixed and will consist of:
- Multiple-choice test questions with a single answer (4 possible answers and only one valid) in which errors are penalized.
- Short questions through which the student must answer or reason through to justify their answer.
INTERACTIVE TEACHING represents 40% of the total grade (4 points)
It will be necessary to achieve at least 50% of the total score in the Theoretical Content section in order to pass the subject.
Hours of personal work of the student, not in person.
Individual study: 54 hours
Elaboration of works: 24 hours
Library or similar activities: 12 hours
TOTAL: 90 hours
Use of the recommended bibliography for the study of the syllabus and the realization of the seminars.
Personalized elaboration of documents for the study of the themes of the program.
Use of the tutoring schedule to answer questions and receive guidance.
The continued study will facilitate the learning process, favoring a better understanding and assimilation of concepts.
Lisa Kay Busch
- Department
- Biochemistry and Molecular Biology
- Area
- Biochemistry and Molecular Biology
- lisa.busch [at] usc.es
- Category
- Professor: Temporary PhD professor
| 05.30.2024 10:00-12:00 | Grupo de examen | Classroom 1 (Building Xoán XXIII) |
| 05.30.2024 10:00-12:00 | Grupo de examen | Classroom 2 (Building Xoán XXIII) |
| 05.30.2024 10:00-12:00 | Grupo de examen | Classroom 3 (Building Xoán XXIII) |
| 05.30.2024 10:00-12:00 | Grupo de examen | Classroom 4 (Building Xoán XXIII) |
| 07.01.2024 10:00-12:00 | Grupo de examen | Classroom 1 (Building Xoán XXIII) |
| 07.01.2024 10:00-12:00 | Grupo de examen | Classroom 2 (Building Xoán XXIII) |
| 07.01.2024 10:00-12:00 | Grupo de examen | Classroom 3 (Building Xoán XXIII) |
| 07.01.2024 10:00-12:00 | Grupo de examen | Classroom 4 (Building Xoán XXIII) |